Inflammatory Bowel Disease Medical & Surgical Options Overview

What are options for medical treatment & Surgery for Ulcerative Colitis and Crohn's Disease and How do they fit in or against Ayurveda?

In the last unit of Email Training about Ayurvedic treatment of Inflammatory Bowel Diseases or IBDs, you knew about .....

My replies to the most relevant questions and Frequently Asked Questions about Ayurvedic Treatment of Ulcerative Colitis & Crohn's Disease.

You will also know about my views how these two protocols - medical and surgical - do fit with Ayurveda.

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Medical Treatment of IBDs - Ulcerative Colitis & Crohn's Disease:

Definitely, I am an Ayurveda doctor and have expertise in Ayurvedic medicine. This information about medical treatment and surgical options  is General and you should always ask your medical consultant about the possible side effects and outcome of medical treatment in short to mid to long term.

Topical Anti-Inflammatory Drugs are simple pain killers and anti-inflammatory that needs direct contact with inflamed surface.

These work on the same principle as Non-Steroid Anti-inflammatory Drugs or pain killers. They relieve the symptoms and inflammation. These do have some side effects but are used in mild to moderate symptoms of Ulcerative Colitis.

5-ASA (5-aminosalicylic acid), also called mesalamine, are similar to aspirin. Several modified compounds are used as drugs that help to prevent its absorption in stomach and small intestine, or make it available in last part of small intestine. Some of them are…

  1. Sulfasalazine – A 5-ASA molecule linked with a sulfapyridine molecule, a Sulfa Antibiotic
  2. 5-ASA compound, Mesalamine, surrounded by an acrylic resin coating (Free from Sulpha Antibiotic)
  3. Lialda (Mesalamine multi matrix, MMX) is a Extended Release Tablet
  4. Apriso: 5-ASA that consists of extended-release Mesalamine granules encased in microcrystalline cellulose
  5. Pentasa: 5-ASA compound Mesalamine inside controlled-release spheres
  6. Olsalazine (Dipentum): two 5-ASA molecules linked together
  7. Balsalazide (Colazal): 5-ASA is linked by a chemical bond to another molecule that is inert
  8. Rowasa Enema is also used to treat mild symptoms. It is 5-ASA compound mesalamine in enema form.

Corticosteroids: Corticosteroids like prednisolone are prescribed as Systemic Steroids. They don’t need direct contact with inflamed surface. They bring down immunity, relieve inflammation and have a good range of side effects on mid to long term use.

Immunomodulator Drugs suppress the body’s immune function by reducing the cells responsible for immunity, or by interfering with proteins important in promoting inflammation. Some examples include 6-Mercaptopurine (6-MP), Azathioprine (Imuran), Methotrexate (Rheumatrex, Trexall) and Cyclosporine (Gengraf, Neoral).

These also do have quite serious side effects in the short term, that you should ask from medical expert while starting the medical treatment.

Surgical Treatment for Ulcerative Colitis:

Surgical removal of gastrointestinal tract or its part is considered when complications of IBDs are present and threaten the life. Some of them are…

  1. Severe Symptoms not responding to drugs
  2. Complications such as Toxic Megacolon
  3. Rupture of Colon
  4. Precancerous changes in Colon
  5. Need for Surgery again within 5 years in Crohn's Disease

When choosing to manage Ulcerative Colitis & Crohn's Disease, it is common to have Ayurvedic treatment along with medical treatment to keep the symptoms in check. Later, gradually, you will move to Ayurveda as main or only treatment.

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